It is primarily aimed to study polymorphisms in vitamin D receptor gene (VDR), which is one of the genetic factors having a role in the formation of lumbar pathologies and/or causing higher incidence of pathologic processes. Secondarily, it is aimed to create pre-data which may help professionals to administer more effective and protective interventions in this area. Without any language preference, we searched US National Library of Medicine National Institutes of Health, Embase, OVID, Cochrane Library database of clinical trials from 1989 to Mar 11 to 2017 Mar 12, and traced all the references of incorporated documents. The data were evaluated by using descriptive statistics. Results were shown as amount or frequency (%). In literature, some vitamin D receptor gene (VDR) polymorphisms have been found in relation to widespread osteochondral diseases. When VDR polymorphisms, vitamin D level and intervertebral disc pathologies have been examined, a satisfactory answer to the question whether specific pathologies could be suppressed in terms of genetics has not been found. By means of this study, it would be understood the genetic factors inhibiting physio pathological process concerning lumbar degenerative disc disease or the genetic factors playing role in identifying physio pathological process related to lumbar degenerative disc disease by defining them. Accordingly, effective and contraceptive treatment of lumbar degenerative disc disease might be ensured soon.
 

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