Bloodstream infections due to bacterial pathogens are a major cause of morbidity and mortality in Bangladesh and other developing countries. In these countries, most patients are treated empirically based on their clinical symptoms. In the perspective of Bangladesh, people are taking medication without consulting a physician and this is the true reason for the emergence of drug resistance. Blood stream infection (BSI) due to bacterial pathogens is a global concern. The aim of this study was to identify the bacterial pathogens causing major bloodstream infections in Brahmanbaria, Bangladesh and determine their antibiotic susceptibility pattern. Two hundred and fifteen blood samples from 215 patients suspected of having BSI were cultured as per standard microbiological procedures. Antimicrobial susceptibility testing was done for bacterial isolates from positive blood cultures. 17 % cases were established as BSI. Staphylococcus aureus were most prevalent (51 %), followed by Enterococcus faecalis (16 %) Escherichia coli (11%), Klebsiella pneumoniae (8 %), Enterobacter spp (5%), Pseudomonas aeruginosa (6%), Proteus vulgaris (3%). Out of 37 positive patients 15 cases were positive for infant which is 41 % of total and the highest number of positive patients was infant and meropenem is most effective drug against all pathogens. The study shows the prevalence of common bacterial pathogens causing BSI and their susceptibility patterns. Such studies provide benefits of instantaneous choice of antibiotic therapy aiming at improved patient management and reduced drug resistance.
 

Download Full Text - PDF