This study was aimed to find out the Prevalence of Tuberculosis in Kohat and lower Orakzai Agency. The survey was conducted at District Headquarter Hospital Kohat and Tehsil Headquarter Hospital Lower Orakzai Agency Kalaya. It was 12 weeks survey which extended from March 2014 to June 2014. Data was collected from the TB Center of the both Hospital. A total of one hundred and six histories were collected for the process of evaluation. Out of a total 106 patients, 59 patients (55.66%) were sputum positive and 47 patients (44.33%) were sputum negative. Among these 106 cases, 52 patients (49.05%) were females and 54 patients (50.94%) were males. Twenty eight individuals (26.41%) were between 1-20 years of age, Forty one individuals (38.67%) were between 21-40 years of age, Twenty nine individuals (27.35%) were between 41-60 years of age, Seven individuals (6.60%) were between 61-80 years of age and only One individual (0.94%) was between 81-100 years of age. Majority of the individuals were between 21-40 ages i.e. 41 (38.67%). Majority of the patients were members of poor, deprived and lower local class. The chief presenting symptoms were productive cough, coughing with blood, fever, weight loss, tiredness but some there were also some cases which could not be identified through symptoms. Sputum AFB positive pulmonary tuberculosis is more in individuals of low socioeconomic group and in females. The patients put their children and family members at risk of tuberculosis infection. For the control of this disease early diagnosis of active disease and their treatment under supervision is important.