In the following report, we discuss a rare case of a huge mass of the thyroid gland that developed in a 45 years old male patient presented with a diffuse neck mass. Imaging shows a large mass of the neck, with no extra thyroid extension. Preoperative diagnosis was made by fine needle aspiration as suspension of TB versus malignancy. Open surgical excision biopsy yielded a definitive diagnosis of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma.

 

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