The ethanolic leaf extract of Eremomastax speciosa was evaluated for its anti-anaemic activity and it possible adverse effect on the Kidney function of Wistar albino rats. The effect of ethanolic extract on haemoglobin concentration, red blood cell count, packed cell volume, white blood cell count and platelet count was investigated. The extract 100 – 300 mgKg-1 demonstrated antianaemic property by significantly (p<0.05) increasing the levels of red blood cell count, haemoglobin level, packed cell volume and white blood cell counts of treated animals. The ethanolic extract of the plant also indicated no adverse effect on the kidney function by non- significantly increasing serum creatinine and urea levels.