In the recent past, uric acid, the end product of Purine metabolism in humans, has been claimed elevated in type 2 diabetic subjects, with a good correlation to diabetic complications. Uric acid is sparingly soluble in body fluids and information regarding its distribution in body fluids particularly blood and urine as well as in plasma and erythrocytes is scanty. A study was undertaken to assess the distribution of uric acid in type 2 diabetic subjects in plasma, erythrocytes and in urine. The results suggest there is an equal distribution and the urinary excretion is significantly reduced.
 

Download Full Text - PDF